Similarly, KEAP1 knockdown has varying effects depending on cancer type, for example, it inhibits metastasis in N87 (gastric cancer) and HCC1954 (breast cancer) cells, but enhances metastasis in HCC1806 and MCF7 (breast cancer) cells, with no impact on ZR-75-1 (breast cancer) cells [62]. This evidence concerns the gene KEAP1 and cancer.