FAAP100 and Friedreich ataxia: FA is also the most frequently inherited bone marrow failure syndrome and originates from the inheritance of pathogenic variants (PVs) in one of any 23 genes (FANCA-FANCX) that operate in the FA/BRCA pathway, responsible for recognizing and repairing DNA interstrand cross-links (ICL), through homologous recombination, an error-free pathway of DNA repair [1,2,3].