It is well known that CD25 is expressed by the neoplastic cells of some hematopoietic/lymphoid neoplasms, such as ALCL, adult T-cell leukemia/lymphoma, hairy cell leukemia, B lymphoblastic leukemia/lymphoma (especially Ph+ or Ph-like type), acute myeloid leukemia, and systemic mastocytosis [17,18,19,20,21,22,23]. The gene discussed is IL2RA; the disease is anaplastic large cell lymphoma.