ACHE and early-onset autosomal dominant Alzheimer disease: The cholinergic action of Bacopa monnieri results in increased acetylcholine levels (acetylcholinesterase inhibition), so special attention should be paid when simultaneously administering Bacopa monnieri extract and acetylcholinesterase inhibitors (AChE-I) currently used in treating Alzheimer’s disease, to avoid a radical increase in acetylcholine levels.