Myricitrin, a flavonoid in fruits and vegetables, lowers the atherogenic index and cardiovascular risk factors and inhibits hepatic 3-hydroxy-3-methylglutaryl-CoA reductase and acyl-CoA:cholesterol acyltransferase activity, improving hypercholesterolemia and MASLD in mice [45]. The gene discussed is HMGCR; the disease is familial hypercholesterolemia.