It is worth mentioning that this study focused solely on the 677C>T polymorphism and did not research other polymorphisms of the MTHFR gene (such as the 1298A>C polymorphism), since there was no proven relation of the MTHFR gene polymorphisms to thyroid cancer, hyperhomocysteinemia or hypothyroidism, except for 677C>T, as previously stated. Here, MTHFR is linked to hypothyroidism.