SNPs within our candidate regions in chromosome 4 (mapped to PPA2 gene), chromosome 6 (mapped to PANDAR/LAP3P2) chromosome 12 (mapped to POU6F1) and chromosome 18 (mapped to CTIF gene), were assigned to genes TET2, CDKN1A, LIMA1 and ACAA2 respectively and as effector genes in the CRC risk meta-GWAS. This evidence concerns the gene PPA2 and colorectal carcinoma.