An example of the locus plot for one of the colocalised regions (mQTL for probe cg12483773 in POU2AF2, COLCA1 and POU2AF3 region) with the CRC meta-GWAS data is presented in Fig. 2 where we observe that mQTL for probe cg12483773 and CRC risk signals shared a common causal variant (rs3087967). Here, POU2AF3 is linked to colorectal carcinoma.