NEDD9 and infection: Interestingly, immunofluorescence staining using LysoTracker to track acidic organelles within macrophages upon ST infection revealed, besides colocalization with NEDD9 (Fig. 2A) a significantly increased intensity of LysoTracker in Nedd9-/- mBMDMs compared to Nedd9wt/wt mBMDMs indicating elevated lysosomal activity in the absence of NEDD9 (Fig. 2F, G).