Another program (Program-2) includes factors such as naïve CD4 + T cells (ThN) in the Tumor, Short-lived plasma (antibody-secreting) B cells (PS) in the Tumor, Natural Killer Cells in General Lymph Nodes, naïve CD4 + T cells in General Lymph Nodes, Activated CD4 + T cells in the Tumor, naïve CD4 + T cells in Tumor Draining Lymph Nodes, Activated CD8 + T cells in Tumor Draining Lymph Nodes, IL2 in Tumor Draining Lymph Nodes, Antigen in Tumor Draining Lymph Nodes and Treg in the Tumor. This evidence concerns the gene CD8A and neoplasm.