As shown in Fig 4, genes (CTCFL, PLAC1, LEMD1, PRAME, CEP55, DKKL1, PBK, ATAD2, and TTK) from the GEPIA2 dataset, and genes (PLAC1, FBXO39, LEMD1, DKKL1, PBK, ATAD2, and TTK) of primary and recurrent GBM from the mRNA_seq693 of the CCGA cohort were not associated significantly with OS in GBM patients. This evidence concerns the gene LEMD1 and glioblastoma.