Ding et al. extended these findings in a murine silicosis model, showing that systemic administration of a miR-125a-5p antagomir restores Th1/Th2 and Treg/Th17 balance, attenuates NF-κB activation, and reduces collagen deposition and lung fibrosis in vivo [46, 47]. The gene discussed is NFKB1; the disease is silicosis.