In this case, we again find that our co-occurring perturbation networks contain many genes previously found to promote or mitigate cancer metastasis, including NF1 knockdown, SOX5 overexpression, CBFB overexpression, TOX4 knockdown, PROX1 overexpression, and EHF knockdown (67, , , , –72). This evidence concerns the gene CBFB and cancer.