CD28 and melanoma: Figure 1A illustrates the MART‐1‐TCR S/MAR vector encoding the α‐ and β‐chain of the melanoma antigen MART‐1 as the GOI, while Figure 1B shows the MCSP CAR S/MAR vector encoding the MCSP‐specific single chain variable fragment (scFv), the hinge region, an intracellular CD3 signaling domain together with a truncated CD28.