2014; Meneses et al. 2021). Because of the low levels in CSF, total length TDP‐43 levels were examined in plasma NDEVs. Enzyme‐linked immunosorbent assay (ELISA) results of TDP‐43 were shown to be significantly increased in AD patients when compared to healthy controls (Zhang et al. 2020). This evidence concerns the gene TARDBP and Alzheimer disease.