In one of the first studies that investigated the content of NDEVs as biomarkers, it was shown that p‐serine 312‐IRS‐1 and p‐pan‐tyrosine‐IRS1 were found in AD patients’ NDEVs and were significantly higher than in DM2 or FTD patient EVs. The gene discussed is IRS1; the disease is frontotemporal dementia.