Table  compares the approximateserum or plasma concentrations of MCP-1, IP-10, and NS1 biomarkersin mild dengue fever and in severe disease (dengue hemorrhagic fever/severedengue). These ranges are only estimates because concentrations varywith the day of illness, patient age, viral serotype, and whetherthe infection is primary or secondary. Taken together, integratinghost biomarker with viral biomarker measurements provides comprehensiveinsights into dengue pathogenesis and progression, and this will helpstratify patients according to their disease severity. This evidence concerns the gene CCL2 and dengue disease.