ATG4A and chronic myelogenous leukemia, BCR-ABL1 positive: Three machine learning algorithms (LASSO, RF, and SVM-RFE) were used for dimensionality reduction, and we identified 11, 11, and 4 variables associated with CML from DEARGs, respectively (Figures 5A–E), including three overlapping diagnostic ARGs (TUSC1, FOXO1, and ATG4A) (Figure 5F).