hs-cTn: High-Sensitivity Cardiac Troponin; MI: Myocardial Infarction; PPV: Positive Predictive Value; NPV: Negative Predictive Value; AUC: Area Under the Curve; CI: Confidence Interval; NT-proBNP: N-terminal pro B-type natriuretic peptide. The gene discussed is NPPB; the disease is myocardial infarction.