Alb, serum albumin; BUN, blood urea nitrogen; Cre, creatinine; eGFR, estimated glomerular filtration rate; GLP-1, glucagon-like peptide 1 receptor agonists; HbA1c, glycated hemoglobin; HNA%_0y, percentage of human non-mercaptalbumin at baseline; LDL-C, low-density lipoprotein cholesterol; MMSE, Mini-Mental State Examination; NDR, no diabetic retinopathy; PPDR or PDR, pre-proliferative or proliferative diabetic retinopathy, or history of photocoagulation/vitreous surgery; SDR, simple diabetic retinopathy; TG, triglyceride; UA, uric acid. The gene discussed is ALB; the disease is diabetic retinopathy.