While the addition of etomoxir did not potentiate the cell death of CH157-MNEV, there was a significant decrease in viability in the CH157MN-NOTCH3 ICD (42.2 ± 2.2% in RSL3 compared to 30.7 ± 3.0% in RSL3 with Eto; p < 0.05), demonstrating that enhanced FAO is protective against ferroptosis in meningioma cells. This evidence concerns the gene NOTCH3 and meningioma.