NTRK1 and arthritic joint disease: NTRK1 has been shown to associate with other conditions related to aging and cognitive decline such as Parkinson’s disease (Liu et al., 2018), early AD subtype (Cozza et al., 2008), arthritis (Hall et al., 2024), and hippocampal volume and cell survival (de Frutos Lucas et al., 2022; Yang et al., 2023), but literature support for the association between NTRK1 and AD directly remains limited.