Figure 5d illustrates the distribution of AD GWAS SNP associations within the NTRK1 locus, highlighting two missense mutations that are marginally associated with AD: rs926103 on the third exon of SH2D2A and rs4399146 on the fifth exon of HDGF (Raney et al., 2024). The gene discussed is SH2D2A; the disease is Alzheimer disease.