SNP-level AD and eQTL associations for three of these genes (RIPK2, NTRK1, RIOK1) related are displayed in Figure 4c, and Figure 4b demonstrates that gene-level fine-mapping identified NTRK1 and RIPK2 as putative drivers with high confidence (PIP=1.00) and RIOK1 with moderate confidence (PIP=0.58). The gene discussed is RIOK1; the disease is Alzheimer disease.