Recent clinical studies have shown that the therapeutic efficacy of cancer has been greatly improved through the renewal of chemotherapeutic drugs, precise radiotherapy, blockade of tumor immune suppression by PD-1 and PD-L1 antibodies, immunotherapy based on chimeric antigen receptor (CAR)-T cell therapy, targeted therapy based on blocking tumor angiogenesis, and autologous stem cell transplantation (146, 147). Here, CD274 is linked to neoplasm.