IFNAR1 and Alzheimer disease: In an animal model of AD, the APPSWE/PS1ΔE9 mouse, mice with ablated type-I IFN signalling (APPSWE/PS1ΔE9 x IFNAR1−/−), display reduced Aβ monomer levels, attenuated microgliosis and levels of pro-inflammatory cytokines that correlates with improved spatial learning and memory performance (Minter et al., 2016b).