The ATLAS score is a widely used tool for assessing CDI severity at diagnosis, that can be used to predict the likelihood of severe outcomes such as colectomy/ileostomy, sepsis, and mortality.14 Although it outperforms other models in predicting CDI outcomes, it does not include some key markers of disease severity, such as CRP.10,14 This case highlights the importance of early recognition and timely treatment of fulminant CDI, the efficacy of FMT as a minimally invasive therapy, and the significant role of CRP in assessing residual colitis and disease resolution. The gene discussed is CRP; the disease is Sepsis.