The comparable LPA and NPA formation in all infected mice on day 14 PI suggests that as the expression level of LPG required for DKK1 production declines in the mammalian host with transformation of the parasite into the amastigote stage, LPG plays a minimal critical role in the formation of platelet-neutrophil aggregates needed for neutrophil infiltration to the infection site. Here, DKK1 is linked to infection.