Against our initial assumption, AhrdCAIR/dCAIR mice showed no defects during this infection and dealt with it more efficiently than wildtype mice, exhibiting lower bacterial levels, less inflammation and increased production of IL-22, a major determinant of barrier protection in this infection (Basu et al., 2012; Li et al, 2018; Melchior et al, 2024). This evidence concerns the gene IL22 and infection.