Human Chorionic Gonadotropin Beta (beta-hCG), the beta subunit of essential heterodimeric developmental glycohormone human Chorionic Gonadotropin (hCG), is an oncofetal antigen expressed primarily in trophoblast cells during embryogenesis and reexpressed in multiple cancer types (Lapthorn et al., 1994; Douglas et al., 2014; Iles 2007). This evidence concerns the gene CGB5 and cancer.