To analyze contributions of single Eph receptors to MHV68 infection, Raji cells were transduced with lentiviruses encoding TwinStrep-tagged Eph receptors including human and murine EphA4 and EphB3 which bind MHV68 gH/gL (Fig 1) and inhibit infection on permissive cell lines (Fig 2). Here, EPHB3 is linked to infection.