ELAVL3 and Alzheimer disease: To further examine the relationship between CE inclusion due to TDP-43 dysfunction and key pathological markers of AD and LATE, we performed a pairwise correlation analysis between CE-containing transcripts (STMN2, UNC13A, ELAVL3, ARHGAP32, CAMK2B, KALRN, PFKP, and SYT7) and disease-associated pathologic proteins, including pTDP-43 alone, pTau/Tau ratio, and Aβ42 (Figure 2A).