In SCLC, OC2 mRNA expression is also significantly higher in tumor tissue compared to adjacent normal lung tissue, as observed in the GSE60052 (Jiang et al. 2016), GSE40275 (Kastner et al. 2012), GSE30219 (Rousseaux et al. 2013), and GSE149507 (Cai et al. 2021) cohorts (Fig. 1A and Supplementary Fig. 1B). Here, ONECUT2 is linked to neoplasm.