Keratoconus is a corneal disorder with a corneal cone-like protrusion.466 In keratoconus patients, the oxidation and antioxidation of corneal epithelium are dysregulated.467–469 Yildiz et al. showed that PINK1 expression was down-regulated in corneal epithelium, suggesting that mitophagy may take part in the pathogenesis of keratoconus.470. The gene discussed is PINK1; the disease is keratoconus.