BCH and α-methyl-D,L-tryptophan are system B0,+ inhibitors, which can inhibit CAA (arginine) and neutral amino acid (leucine) transport by the system B0,+ transporter protein, ATB0,+ (SLC6A14) when expressed in xenopus oocytes or breast cancer cells [42–44]. The gene discussed is SLC6A14; the disease is breast cancer.