To evaluate the effector function of total and IC‐expressing CD4+ and CD8+ T‐cell subsets, we assessed their expression levels of proinflammatory cytokines (IFN‐γ, TNF‐α, GM‐CSF, IL‐17) and anti‐inflammatory cytokine IL‐10, in both PB and WL‐GBM samples. The gene discussed is TNF; the disease is glioblastoma.