Accordingly, the frequencies of CD69 and CD103 expressing cells were dramatically higher in both CD4+ and CD8+ T cells’ population from tumor samples than from PB, both in the case of W‐L GBM (Figure 2A–C) and in the case of all the three layers of 5‐ALA resected GBM, compared with PB (Figure 2D–F). This evidence concerns the gene CD4 and neoplasm.