Eleven samples were assigned to another methylation class with a high confidence score (extraventricular neurocytoma, rosette-forming glioneuronal tumor, pineocytoma, pineoblastoma, CNS tumor with EP300::BCOR(L1) fusion, and CNS neuroblastoma with FOXR2 activation) or yielded low prediction scores (n = 5; Fig. 3A, Supplementary Table 1). This evidence concerns the gene BCOR and central nervous system neoplasm.