LTR12C yields promising features in the action against cancer: first, its strength as a gene promoter can enhance GTA-p63 pro-apoptotic functions by sustaining its transcription; second, by constituting the 5′ end of GTA-p63 transcripts, it can be translated in antigenic epitopes useful for the development of specific vaccines against glioblastoma. The gene discussed is TP63; the disease is cancer.