While numbers of proliferating progenitor cells and maturating neuroblasts as well as apoptosis in the DG of Casp8ΔIEC mice were comparable to those in the DG of Casp8fl mice, minimal changes in the expression of NeuN within maturating DCX+ neuroblasts are possible, as mice age and ileocolitis progresses. The gene discussed is RBFOX3; the disease is ileocolitis.