Besides absolute numbers, beginning neuronal differentiation of proliferating Mcm2+ progenitor cells indicated by the percentage of expression of the immature neuroblast marker DCX was not altered by ileocolitis (Casp8fl vs. Casp8ΔIEC 14 weeks: 70.9 ± 2.6% vs. 68.4 ± 5.6%, p = 0.923; 24 weeks: 59.6 ± 8.5% vs. 61.0 ± 6.9%, p > 0.999; Figure 3C). This evidence concerns the gene MCM2 and ileocolitis.