GDNF and ileocolitis: In line with the maintained stages of neurogenesis detected by histology, we did not observe alterations in the expression of Bdnf (Casp8fl vs. Casp8ΔIEC 14 weeks: 1.0 ± 0.6 vs. 0.9 ± 0.3, p = 0.673; 24 weeks: 1.0 ± 0.3 vs. 0.8 ± 0.4, p = 0.472; Figure 3F), Gdnf (Casp8fl vs. Casp8ΔIEC 14 weeks: 1.0 ± 1.0 vs. 0.8 ± 0.5, p = 0.665; 24 weeks: 1.0 ± 0.7 vs. 1.1 ± 1.2, p = 0.920; Figure 3F), and Igf1 (Casp8fl vs. Casp8ΔIEC 14 weeks: 1.0 ± 1.0 vs. 1.0 ± 0.6, p = 0.966; 24 weeks: 1.0 ± 0.4 vs. 0.9 ± 0.5, p = 0.686; Figure 3F) between mice with ileocolitis and controls in both age cohorts.