PRSS16 and colitis: Our results are consistent with those reported by Roig et al., 2018 [18] using extracellular vesicles from F. hepatica (FhEV) and were also similar to those obtained by others that used defined recombinant antigens from Schistosoma mansoni (GST28) [36], Trichinella spiralis (TsSp) [37], and Ascaris lumbricoides (Al-CPI) [38] in colitis mouse models.