BNIP3 and acute kidney injury: A study conducted on ischemic AKI in mouse models and gentamicin-induced AKI in the zebrafish model demonstrated that cobaltosilicate oxide-polyethylene glycol-triphenylphosphine (COPT) nanoparticles ameliorate the transition from acute to chronic kidney disease by inducing BNIP3-mediated mitophagy [133].