The TNFα signaling pathway via NF-κB, Dectin1-mediated noncanonical NF-κB signaling, and the TNFR2 noncanonical NF-κΒ pathway, all involved in cellular immune and inflammatory pathways, are 1.9- (HALLMARK: FDRq <0.001), 1.7- (REACTOME: FDRq = 0.095), and 1.7-fold (REACTOME: FDRq = 0.092) enriched, respectively, in the HF-fed LFABP−/− mice, relative to WT. This evidence concerns the gene TNFRSF1B and hydrops fetalis.