LAMB2 and hydrops fetalis: Changes in multiple ECM-related pathways were found in the iWAT of HF-fed LFABP−/− mice, including collagen formation and degradation, the biosynthesis of collagen and modifying enzymes, the assembly of collagen fibrils and other multimeric structures, the crosslinking of collagen fibrils, the degradation of the ECM, the activation of matrix metalloproteinases, ECM proteoglycans, ECM organization, and laminin interactions (Table 2, Table S2 and Figure 4b,c).