Interestingly, PR/SET domain 1 (Prdm1, also known as Blimp1), a DNA-binding protein expressed in neonatal IECs or induced in AIDS patients (36, 37), acts as a tether/sequestration factor by recruiting XR_001779380 to form the Prdm1/Stat1/Pias1 complex. This evidence concerns the gene PRDM1 and AIDS.