CCR2 and infection: In the lung at 4 weeks post-infection, accumulation of Ly6Cpos macrophages and DCs declined by more than 80% in CCR2-deficient (Ccr2RFP/RFP) and DKO mice, while CX3CR1-deficient (Cx3cr1GFP/GFP) mice had preserved trafficking relative to Het mice (Fig. 2A; Fig. S5A).