Another study revealed that let‐7c‐5p promoted anti‐inflammatory and pro‐osteogenic effects in DPSCs by restoring the proliferation and osteogenic differentiation impaired by pulpitis through the inhibition of high mobility group A2 (HMGA2)/phosphatidylinositol 3‐kinase (PI3K)/Akt signalling (Yuan et al., 2019). Here, AKT1 is linked to pulpitis.