It was found that Caspase‐3 was upregulated 4.5‐fold in the CB‐AKK group compared with the control group (p < 0.0001), and Ki‐67 decreased by 0.5‐fold (p = 0.0428), indicating that CB‐AKK treatment inhibited tumor cell proliferation and significantly promoted tumor cell apoptosis. Here, MKI67 is linked to neoplasm.