IL6 and myocardial infarction: Th17 cells have also been detected in the infarcted myocardium following MI, where they exacerbate inflammation and tissue damage by secreting pro-inflammatory cytokines such as interleukin (IL)-6 and IL-23; promoting the recruitment of immune cells, including neutrophils and macrophages, amplifying inflammatory responses, and worsening myocardial injury (33).