CD8A and Abnormal intestine morphology: Among CD8 T cells, an increased proportion of total CD8 T cells—and in particular effector memory CD8 T cells (TEM) and terminal effector cells re-expressing CD45RA (TEMRA)—has been reported in CVIDc patients with autoimmune cytopenia (9, 10) and local expansion and alteration of circulating CD8+ T cells in enteropathy (11).