Fecal lactoferrin and calprotectin are commonly used to screen for immune checkpoint inhibitor-induced colitis (23), with calprotectin being particularly useful for assessing treatment response and reducing the need for repeat endoscopies (24).In addition to these biomarkers, baseline absolute counts of neutrophils, lymphocytes, monocytes, eosinophils, and basophils, platelet counts, and changes in white blood cells, lymphocytes, and eosinophils during follow-up are associated with an increased risk of immune-related adverse events. This evidence concerns the gene LTF and colitis.