In the fully adjusted model, which included age, gender, smoking, hypertension, diabetes, CKD, ApoA1, ApoB, albumin, uric acid, eGFR, fibrinogen, LVEF, and Gensini score, Lp(a) remained linearly and positively associated with all-cause (Figure 2A) and cardiovascular (Figure 2B) mortality (P-nonlinear = 0.528 and 0.859). This evidence concerns the gene APOA1 and hypertensive disorder.