RhoA/ROCK pathway is implicated in various diseases, including ovarian cancer (Wei et al., 2021), chronic headache (Jing et al., 2019), traumatic brain injury (Mulherkar and Tolias, 2020), Parkinson’s disease (Iyer et al., 2021), stroke (Lu et al., 2023)and other neurological disorders. The gene discussed is RHOA; the disease is ovarian cancer.