These transcripts include ESYT2, known to play a role in synaptic growth and neurotransmission, LGI2, involved in inhibitory synapse assembly [45,46], NAB1, a transcriptional repressor with a role in synaptic active zone assembly [47,48], PHLDA1, involved in injury response [49], CLCC1, involved in misfolded protein clearance [50], THAP1, implicated in dystonia (DYT6, # 602629) [51], and SLITRK4, involved in controlling excitatory and inhibitory synapse formation [52]. The gene discussed is LGI2; the disease is Dystonia.