CXCR2 and endothelial dysfunction: The critical roles of CCR2 and CXCR2 in further disruptions, such as endothelial dysfunction, smooth muscle cell proliferation, angiogenesis, and WBC infiltration/activation/adhesion highlight the importance of these receptors in vascular atherosclerosis (Speyer & Ward, 2011; Zernecke & Weber, 2009).