Future studies will focus on elucidating whether AREG directly induces angiogenesis or acts indirectly by modulating pro-angiogenic factors such as VEGF and FGF, and further investigate the role of the complete signaling cascade, including AREG and FoxM1, in post-myocardial infarction angiogenesis. Here, FOXM1 is linked to myocardial infarction.