However, by using adoptive transfer of AREG-overexpressing Tregs, the study investigated the effect of AREG+Tregs on post-myocardial infarction angiogenesis, and conducted rescue experiments by downregulating FoxM1 in myocardium or CMECs using lentivirus carrying small interfering RNA both in vivo and in vitro. This evidence concerns the gene FOXM1 and myocardial infarction.